As for Liverpool, it’s all about getting their season back on track after being humiliated 7-2 by Aston Villa before the international break. Should they suffer a rare defeat to their nearest and dearest, serious questions will be asked about whether Jürgen Klopp’s side has the bottle to retain their title. And he won’t like that one bit.

This showdown is about more than bragging rights. It could be the start of a major momentum shift on Merseyside. Before the drama kicks off, why not whet your appetite by looking back at five classic encounters between these most ferocious of foes – then head to the bottom of the page to play our special football quiz…

1. A Cup classic (1991)

Everton 4-4 Liverpool

An unforgettable match in more ways than one, this was the last time Kenny Dalglish managed Liverpool before his remarkable return in 2011. This FA Cup fifth-round replay saw the Reds take the lead no fewer than four times, but a late rally from Everton meant the Toffees forced a second replay (which they won 1-0). In a passionate game bursting with great moments, John Barnes’ exquisite curler into the top corner for Liverpool stands out.

2. Clashes, cards and Campbell (1999)

Liverpool 0-1 Everton

Everton’s last Premier League triumph at Anfield may have been a low-scoring affair, but it certainly wasn’t without incident. Kevin Campbell’s smart finish early on separated the sides during a fiery 90 minutes, with Reds goalkeeper Sander Westerveld and Toffees striker Francis Jeffers sent off for scrapping like it was closing time. Steven Gerrard was also given his marching orders, while Steve Staunton ended up in goal for Liverpool. So a textbook Merseyside derby then.

3. The Toffees trounce their rivals (2006)

Everton 3-0 Liverpool

This sweetest of victories for Everton saw the Toffees record their biggest win over Liverpool in 42 years. The hosts clicked brilliantly in attack, with Tim Cahill and Andy Johnson among the goals, but they were also helped by the kind of defending that would make a Sunday league team blush. Pepe Reina had a particular ’mare, while Jamie Carragher also took leave of his senses for large parts of the match.

4. Maestro McAllister gives Everton the blues (2001)

Everton 2-3 Liverpool

A sure-fire way to make yourself an instant Liverpool legend is to score a last-minute winner at Goodison. Just ask Gary McAllister. With the Reds having led twice in this full-blooded Premier League encounter, the wily Scot curled in an ingenious free kick late in the day to give his side the three points. Liverpool’s season went from good to iconic as they ended up clinching the FA Cup, UEFA Cup and League Cup under manager Gérard Houllier.

5. Goals galore at Goodison (2013)

Everton 3-3 Liverpool

Roberto Martinez’s Everton and Brendan Rodgers’ Liverpool both swashbuckled their way through the 2013-14 season, so it was no surprise they served up this absolute classic. Romelu Lukaku thought he had secured a win for the hosts with eight minutes remaining in this back-and-forth blockbuster, only for Daniel Sturridge to snatch a point for the visitors at the death. Oh, and Kevin Mirallas should have been sent off for a shocking challenge on Luis Suárez. It was a Merseyside derby, after all.

Can you beat our 2006-07 Premier League quiz?

The 2006-07 campaign was the last time Everton beat Liverpool in the league. But how much do you remember from that season? Take our quiz to test your knowledge…

When is Everton v Liverpool on TV?

Coverage of Everton’s Premier League clash with Liverpool at Goodison Park starts at 11.30am on Saturday 17 October on BT Sport 1 HD (CH 527).

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